USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q15056 USC-OGP 2-DE database:  Q15056 Q15056 General information about the entry View entry in simple text format Entry name IF4H_HUMAN Primary accession number Q15056 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Eukaryotic translation initiation factor 4H; Short=eIF-4H; AltName: Full=Williams-Beuren syndrome chromosomal region 1 protein;. Gene name Name=EIF4H Synonyms=KIAA0038, WBSCR1, WSCR1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1253: pI=6.35; Mw=30714 SPOT OGP-1258: pI=6.30; Mw=30200 Cross-references UniProtKB/Swiss-Prot Q15056; IF4H_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name IF4H_HUMAN Primary accession number Q15056 Secondary accession number(s) A8K3R1 D3DXF6 D3DXF8 Sequence was last modified on  January 23, 2007 (version 5) Annotations were last modified on  March 15, 2017 (version 172) Name and origin of the protein Description RecName: Full=Eukaryotic translation initiation factor 4H; Short=eIF-4H; AltName: Full=Williams-Beuren syndrome chromosomal region 1 protein; Gene name Name=EIF4H Synonyms=KIAA0038, WBSCR1, WSCR1 Encoded on Name=EIF4H; Synonyms=KIAA0038, WBSCR1, WSCR1 Keywords Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Host-virus interaction; Initiation factor; Methylation; Phosphoprotein; Protein biosynthesis; Reference proteome; RNA-binding; Williams-Beuren syndrome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF045555; AAF75557.1; -; Genomic_DNA EMBL AF045555; AAC04859.2; -; Genomic_DNA EMBL D26068; BAA05063.1; ALT_INIT; mRNA EMBL AK290676; BAF83365.1; -; mRNA EMBL CH471200; EAW69616.1; -; Genomic_DNA EMBL CH471200; EAW69615.1; -; Genomic_DNA EMBL CH471200; EAW69617.1; -; Genomic_DNA EMBL CH471200; EAW69618.1; -; Genomic_DNA EMBL CH471200; EAW69619.1; -; Genomic_DNA EMBL BC010021; AAH10021.1; -; mRNA EMBL BC021214; AAH21214.1; -; mRNA EMBL BC066928; AAH66928.1; -; mRNA CCDS CCDS5564.1; -. [Q15056-1]; . CCDS CCDS5565.1; -. [Q15056-2]; . RefSeq NP_071496.1; NM_022170.1. [Q15056-1]; . RefSeq NP_114381.1; NM_031992.1. [Q15056-2]; . UniGene Hs.520943; -; . ProteinModelPortal Q15056; -; . SMR Q15056; -; . BioGrid 113297; 56; . IntAct Q15056; 16; . MINT MINT-5002829; -; . STRING 9606.ENSP00000265753; -; . BindingDB Q15056; -; . ChEMBL CHEMBL1293274; -; . iPTMnet Q15056; -; . PhosphoSitePlus Q15056; -; . BioMuta EIF4H; -; . DMDM 18276665; -; . EPD Q15056; -; . MaxQB Q15056; -; . PaxDb Q15056; -; . PeptideAtlas Q15056; -; . PRIDE Q15056; -; . TopDownProteomics Q15056-1; -. [Q15056-1]; . TopDownProteomics Q15056-2; -. [Q15056-2]; . DNASU 7458; -; . Ensembl ENST00000265753; ENSP00000265753; ENSG00000106682. [Q15056-1]; . Ensembl ENST00000353999; ENSP00000265754; ENSG00000106682. [Q15056-2]; . GeneID 7458; -; . KEGG hsa:7458; -; . UCSC uc003uad.2; human. [Q15056-1]; . CTD 7458; -; . DisGeNET 7458; -; . GeneCards EIF4H; -; . HGNC HGNC:12741; EIF4H; . HPA HPA030542; -; . MIM 603431; gene; . neXtProt NX_Q15056; -; . OpenTargets ENSG00000106682; -; . PharmGKB PA162384997; -; . eggNOG KOG0118; Eukaryota; . eggNOG COG0724; LUCA; . GeneTree ENSGT00530000063406; -; . HOGENOM HOG000013063; -; . HOVERGEN HBG018193; -; . InParanoid Q15056; -; . OMA PRTVSEP; -; . OrthoDB EOG091G0PIF; -; . PhylomeDB Q15056; -; . TreeFam TF313897; -; . Reactome R-HSA-156827; L13a-mediated translational silencing of Ceruloplasmin expression; . Reactome R-HSA-72649; Translation initiation complex formation; . Reactome R-HSA-72662; Activation of the mRNA upon binding of the cap-binding complex and eIFs; and subsequent binding to 43S; . Reactome R-HSA-72702; Ribosomal scanning and start codon recognition; . Reactome R-HSA-72706; GTP hydrolysis and joining of the 60S ribosomal subunit; . ChiTaRS EIF4H; human; . GeneWiki EIF4H; -; . GenomeRNAi 7458; -; . PRO PR:Q15056; -; . Proteomes UP000005640; Chromosome 7; . Bgee ENSG00000106682; -; . CleanEx HS_EIF4H; -; . Genevisible Q15056; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0016281; C:eukaryotic translation initiation factor 4F complex; TAS:ProtInc; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell; . GO GO:0005844; C:polysome; IBA:GO_Central; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0004386; F:helicase activity; TAS:Reactome; . GO GO:0000166; F:nucleotide binding; IEA:InterPro; . GO GO:0043024; F:ribosomal small subunit binding; IBA:GO_Central; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0033592; F:RNA strand annealing activity; IBA:GO_Central; . GO GO:0034057; F:RNA strand-exchange activity; IBA:GO_Central; . GO GO:0008135; F:translation factor activity; RNA binding; TAS:ProtInc GO GO:0003743; F:translation initiation factor activity; IBA:GO_Central; . GO GO:0002181; P:cytoplasmic translation; IBA:GO_Central; . GO GO:0048589; P:developmental growth; IEA:Ensembl; . GO GO:0097010; P:eukaryotic translation initiation factor 4F complex assembly; IBA:GO_Central; . GO GO:0001731; P:formation of translation preinitiation complex; IBA:GO_Central; . GO GO:0006446; P:regulation of translational initiation; TAS:ProtInc; . GO GO:0019953; P:sexual reproduction; IEA:Ensembl; . GO GO:0006413; P:translational initiation; TAS:Reactome; . GO GO:0016032; P:viral process; IEA:UniProtKB-KW; . CDD cd12401; RRM_eIF4H; 1; . Gene3D 3.30.70.330; -; 1; . InterPro IPR034229; eIF4H_RRM; . InterPro IPR012677; Nucleotide-bd_a/b_plait; . InterPro IPR000504; RRM_dom; . Pfam PF00076; RRM_1; 1; . SMART SM00360; RRM; 1; . SUPFAM SSF54928; SSF54928; 1; . PROSITE PS50102; RRM; 1; .

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